Rubest10mg
Type:30 Tablets
Generic Name:Rupatadine
Manufacturer:Benham Pharmaceuticals Ltd.
Price:৳300.00
Indication
Allergic rhinitis, Chronic idiopathic urticaria
Adult Dose
Oral Allergic rhinitis; Chronic idiopathic urticaria Adult: 10 mg (1 tablet) once daily.
Child Dose
Oral Allergic rhinitis; Chronic idiopathic urticaria Tablet Child > 12 years: 10 mg (1 tablet) once daily. Children: Use of Rupatadine is not recommended in patients less than 12 years of age. Syrup: Children aged 2 to 11 years: Children weighing 10 kg to less than 25 kg: 1/2 teaspoonful (2.5 ml) syrup once a day with or without food. Children weighing 25 kg or more: 1 teaspoonful (5ml) of syrup once a day with or without food.
Contraindication
Hypersensitivity. Avoid alcohol.
Mode of Action
Rupatadine acts as a long-acting, non-sedative antagonist at histaminergic H1-receptors. Rupatadine also antagonises the platelet-activating factor (PAF). Both histamine and PAF cause bronchoconstriction and lead to an increase in the vascular permeability, acting as mediators in the inflammatory process.
Precaution
Renal or hepatic insufficiency. May impair ability to drive or operate machinery. Pregnancy, lactation. Elderly, children <12 yr.
Side Effect
Headache, somnolence, fatigue/asthenia.
Interaction
Increased CNS depressant effects when used with CNS depressants or alcohol.
