
Mesagut400mg
Type:Tablet
Generic Name:5 Aminosalicylic Acid (Mesalamine)
Manufacturer:Aristopharma Limited
Price:৳7.60
Indications
Treatment of mild to moderately active Ulcerative Colitis & Crohn’s Disease. Maintenance of remission of Ulcerative Colitis. Maintenance of remission of Crohn’s disease.
Pharmacology
The mechanism of action of5 Aminosalicylic Acid (Mesalamine) is unknown, but appears to be topical rather than systemic. Mucosal production of Arachidonic Acid metabolites, both through the cyclooxygenase pathways, that is, prostanoids, and through the lipoxygenase pathways, that is, leukotrienes and hydroxyeicosatetraenoic acids, is increased in patients with chronic infammatory bowel disease. Mesalamine diminishes infammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon.





