Optibet 0.25%0.25%
Type:5ml drop
Generic Name:Betaxolol 0.25% Eye prep
Manufacturer:Jayson Pharmaceuticals Ltd.
Price:৳151.00
Indication
Glaucoma, Ocular hypertension
Adult Dose
Ophthalmic Open-angle glaucoma Adult: Instil 1 drop of 0.25% solution bid. Ocular hypertension Adult: Instil 1 drop of 0.25% solution bid.
Child Dose
Ophthalmic Open-angle glaucoma Child: Instil 1 drop of 0.25% solution bid. Ocular hypertension Child: Instil 1 drop of 0.25% solution bid.
Contraindication
Hypersensitivity. Sinus bradycardia, cardiogenic shock, overt cardiac failure. Pregnancy .
Mode of Action
Betaxolol is a cardioselective Beta-blocker which has greater affinity for ?1-receptors and has little or no effect on ?2-receptors. It lacks intrinsic sympathomimetic but has little membrane-stabilising activity. It also causes the reduction of intraocular pressure by decreasing the production of aqueous humour.
Precaution
DM, renal or hepatic impairment. May mask signs of hypoglycemia & hyperthyroidism. Gradual withdrawal is recommended. Children. Lactation.
Side Effect
>10% Ocular effects Short term discomfort (<25%) Frequency Not Defined Ocular Blurred vision,Corneal punctate keratitis,Itching and/or foreign body sensation erythema,Inflammation,Ocular pain and/or discharge,Ocular drynes,Photophobia Systemic Bradycardia, congestive heart failure, heart block,Depression, dizziness, headache, insomnia, lethargy, vertigo,Hair loss, hives, toxic epidermal necrolysis Glossitis,Bronchospasm, dyspnea,Increase in signs and symptoms of myasthenia gravis
Pregnancy Category Note
Pregnancy Category: C Lactation: Excretion in milk unknown; use with caution
Interaction
Increased risk of bradycardia w/ digitalis glycosides. May cause mydriasis w/ epinephrine. Potential additive effect w/ oral Ca channel blockers, ?-adrenergic blockers, antiarrhythmics (including amiodarone), parasympathomimetics, guanethidine. Increased risk of myocardial depression and hypotension w/ peripheral muscle relaxants (e.g. tubocurarine).
