Sevirax3%
Type:5gm tube
Generic Name:Acyclovir 3% Eye prep
Manufacturer:Gaco Pharmaceuticals(G.A Company Ltd)
Price:৳70.21
Indication
As 3% Eye oint: Apply 5 times/day until 3rd day of complete healing.
Administration
Probenecid, cimetidine and mycophenolate mofetil may increase the plasma concentration of aciclovir. Increased nephrotoxic effects w/ drugs that affect renal physiology (e.g. ciclosporin, tacrolimus).
Adult Dose
Renal impairment. Pregnancy, lactation. Neurological abnormalities with significant hypoxia, serious hepatic or electrolyte abnormalities. Maintain adequate hydration.
Renal Dose
Activity against HSV types I and II and varicella-zoster virus is due to intracellular conversion of aciclovir to the monophosphate by viral thymidine kinase with subsequent conversion to the diphosphate and active triphosphate by cellular enzymes. This active form inhibits viral DNA synthesis and replication by interfering with viral DNA polymerase enzyme and being incorporated into viral DNA.
Precaution
Herpes simplex keratitis
Pregnancy Category Note
Eye application may produce stinging, superficial punctate keratopathy, blepharitis or conjunctivitis.
Interaction
Hypersensitivity.
Alternative brand of Sevirax
Clovir Ointment- 3%
- Eye Ointment
- Acyclovir 3% Eye prep
Price: ৳110.00
The Ibn Sina Pharmaceutical Ind. Ltd.