Alestin10mg
Type:Tablet
Generic Name:Ebastine
Manufacturer:Novelta Bestway Pharmaceuticals Ltd.
Price:৳6.00
Indication
Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria
Administration
May be taken with or without food.
Adult Dose
Oral Allergic conditions Adult: 10-20 mg once daily.
Child Dose
Oral Allergic conditions Child: >6 yr: 5 mg once daily.
Contraindication
Hypersensitivity, cardiac arrhythmias.
Mode of Action
Ebastine, a piperidine derivative, is a long-acting, nonsedating, second-generation histamine receptor antagonist that binds preferentially to peripheral H1 receptors. It is metabolised to active metabolite, carebastine. It has antihistaminic, antiallergic activity and prevents histamine-induced bronchoconstriction. It does not have significant sedative or antimuscarinic actions.
Precaution
Caution is advised when used in hepatic impairment, renal insufficiency, QTc interval prolongation. Pregnancy, lactation.
Side Effect
Headache, dry mouth, drowsiness, pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea, insomnia.
Interaction
Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of ebastine and cause QTc interval prolongation.
